Clinical Features
♦ It occurs during childhood or in adults.
♦ Initially there is presence of papules over the skin which
is red in color later on they become purple brown or gray
in color.
♦ Changes in nails are also seen such as splintering, longitudinal streaking and fissuring.
♦ White papule occurs in oral cavity over hard and soft palate, tongue and gingiva. It is rough on palpation.
Histopathology
♦ Histopathology reveals hyperkeratosis, papillomatosis,
acanthosis and benign dyskeratosis.
♦ Benign dyskeratosis show typical cells, i.e. corps ronds
and grains
♦ Corps ronds: These cells are larger than normal squamous
cells and have round homogeneous basophilic nucleus
with dark eosinophilic cytoplasm and distinct cell membrane. They are seen in granular layer and superficial
spinous cell layer.
♦ Grains: Small, elongated, parakeratotic cells present in
keratin layer.
